Prosaikogenin G

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Prosaikogenin G 是从 Beleurum bicaule Helm（伞形科）的根中分离出来的化合物，是胃肠道中柴胡皂苷 d 的衍生物，对血管紧张素 II 诱导的系膜细胞增殖具有显着的抑制作用。

Prosaikogenin G is a compound isolated from the roots of Buleurum bicaule Helm (Apiaceae) and id a derivative of Saikosaponin d in the gastrointestinal tract, exhibiting a significant inhibitory effect on angiotensin II-induced proliferation of mesangial(In Vitro):Prosaikogenin?G holds a protective effect on the kidney for their down-regulated activity to angiotensin II (1 μM)-induced rat mesangial cell line (MC) proliferation at contentration of 25 or 50 μM, and does not rendered injury to the normal MC .

Prosaikogenin G (25, 50 μM) has protective action on the kidney for their down-regulated activity to the rat mesangial cell line (MC) proliferation induced by Ang II (1 μM), and does not exhibit injury to the normal MC.

——

——

Endocrinology/Hormones

RAAS

RAAS

——

——

99365-23-8

618.84

C36H58O8

>98% (HPLC)

In Vitro:?DMSO : 50 mg/mL (80.80 mM)

C[C@H]1O[C@@H](O[C@H]2CC[C@@]3(C)[C@@H](CC[C@]4(C)[C@@H]3C=C[C@]35OC[C@@]6(CCC(C)(C)C[C@@H]36)[C@H](O)C[C@@]45C)[C@]2(C)CO)[C@H](O)[C@@H](O)[C@H]1O

——

(-20℃)

With Ice Pack

≥ 2 years